The Lacuna Project

lacuna (n.) a gap in a record where something should be

Independent research. Not affiliated with any government, agency, or company.

Exhibit 094

Expression of concern: Efficacy of paroxetine in the treatment of adolescent major depression

Exhibit 094 ยท Journal notice

Expression of concern: Efficacy of paroxetine in the treatment of adolescent major depression

The Journal of the American Academy of Child and Adolescent Psychiatry attached an expression of concern to the 2001 Study 329 article (online 30 September 2025; 2026 Jun;65(6):852; PMID 41925712). An expression of concern is not a retraction.

Source
Journal of the American Academy of Child and Adolescent Psychiatry
Date
Online 30 September 2025; June 2026 issue (vol. 65, no. 6, p. 852)
Grade
Primary record
Document
https://doi.org/10.1016/j.jaac.2025.09.032
Accessed
2026-11-09
Cited by
Findings citing this exhibit

Cited by

Finding MED-4.2
Peer-reviewed A 2001 article reported paroxetine effective and well tolerated in depressed adolescents. A 2015 reanalysis of the same trial's records found no advantage over placebo on the prespecified outcomes and counted 11 paroxetine patients with suicidal or self-injurious behavior where the article had counted five.